EGF Monoclonal / Janelia Fluor 549 / RM0078-2M13

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-21708JF549 (View supplier product page)
Size 0.1 ml
Price $559.00
Antigen EGF
Clone RM0078-2M13
Host Rat
Isotype IgG2
Conjugate Janelia Fluor 549
Target Species Mouse
Applications IHC, IHC-P
Description This was produced from a hybridoma (mouse myeloma fused with spleen cells from a rat immunized with mouse recombinant EGF.
About EGF and Janelia Fluor 549
EGF This gene encodes a member of the epidermal growth factor superfamily. The encoded preproprotein is proteolytically processed to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding with high affinity to the cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
Janelia Fluor 549 Janelia Fluor® 549 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 549 has an excitation peak at 549 nm and an emission peak at 571 nm.
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Janelia Fluor 549 Excitation and Emission Spectra