CYP1B1 Monoclonal / Janelia Fluor 549 / V96

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-50191JF549 (View supplier product page)
Size 0.1 ml
Price $449.00
Antigen CYP1B1
Clone V96
Host Mouse
Isotype IgG1 κ
Conjugate Janelia Fluor 549
Target Species Human, Mouse, Rat
Applications IHC
Description Does not react with CYP1A1.
About CYP1B1 and Janelia Fluor 549
CYP1B1 This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. [provided by RefSeq, Jul 2008]
Janelia Fluor 549 Janelia Fluor® 549 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 549 has an excitation peak at 549 nm and an emission peak at 571 nm.
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Janelia Fluor 549 Excitation and Emission Spectra