Alkaline Phosphatase Monoclonal / Janelia Fluor 549 / H17E2

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB600-750JF549 (View supplier product page)
Size 0.1 ml
Price $499.00
Antigen Alkaline Phosphatase
Clone H17E2
Host Mouse
Isotype IgG1
Conjugate Janelia Fluor 549
Target Species Human
Applications FC, IHC, IHC-Fr
Description This recognises human placental alkaline phosphate. The has been widely used in immunolocalisation studies of germ cell tumours and may also be used in ELISA based assays for the measurement of soluble PLAP.
About Alkaline Phosphatase and Janelia Fluor 549
Alkaline Phosphatase This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects. [provided by RefSeq, Oct 2015]
Janelia Fluor 549 Janelia Fluor® 549 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 549 has an excitation peak at 549 nm and an emission peak at 571 nm.
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Janelia Fluor 549 Excitation and Emission Spectra