GSAP Polyclonal / HRP /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-78400H (View supplier product page)
Size 0.1 ml
Price $449.00
Antigen GSAP
Clone
Host Rabbit
Isotype IgG
Conjugate HRP
Target Species Human
Applications WB
Description Rabbit GSAP antibody [HRP] detects Human
About GSAP and HRP
GSAP Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease (AD; MIM 104300). Formation of amyloid-beta is catalyzed by gamma-secretase (see PSEN1; MIM 104311), a protease with numerous substrates. PION, or GSAP, selectively increases amyloid-beta production through a mechanism involving its interaction with both gamma-secretase and its substrate, the amyloid-beta precursor protein (APP; MIM 104760) C-terminal fragment (APP-CTF) (He et al., 2010 [PubMed 20811458]).[supplied by OMIM, Nov 2010]
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HRP Excitation and Emission Spectra