ATM Monoclonal / HRP / 10H11.E12

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-306H (View supplier product page)
Size 0.1 ml
Price $519.00
Antigen ATM
Clone 10H11.E12
Host Mouse
Isotype IgG1 κ
Conjugate HRP
Target Species Canine (Negative), Human, Mouse, Rat
Applications WB, IHC, IHC-P
Description Mouse ATM antibody reacts with Human, Mouse, Rat, Canine (Negative) [HRP]
About ATM and HRP
ATM The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010]
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HRP Excitation and Emission Spectra