APC Monoclonal / HRP / ALi 12-28

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-667H (View supplier product page)
Size 0.1 ml
Price $509.00
Antigen APC
Clone ALi 12-28
Host Mouse
Isotype IgG1
Conjugate HRP
Target Species Human
Applications WB, IHC, IHC-Fr
Description This recognises the N-terminal region of the APC protein.
About APC and HRP
APC This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Mutations in the APC gene have been found to occur in most colorectal cancers. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product. [provided by RefSeq, Dec 2019]
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HRP Excitation and Emission Spectra