FANCD2 Monoclonal / DyLight 755 / 1290C
FANCD2 Monoclonal / DyLight 755 / 1290C
Product Details
Supplier | Novus Biologicals, a Bio-Techne brand | |
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Catalog #: | NBP2-61930IR (View supplier product page) | |
Size | 0.1 ml | |
Price | $499.00 | |
Antigen | FANCD2 | |
Clone | 1290C | |
Host | Rabbit | |
Isotype | IgG | |
Conjugate | DyLight 755 | |
Target Species | Human, Mouse, Rat | |
Applications | WB, Knockout Validated |
About FANCD2 and DyLight 755
FANCD2 | The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016] | |
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DyLight 755 | DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy. |
Citations
Reviews & Ratings
DyLight 755 Excitation and Emission Spectra
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