CACNA1H Monoclonal / DyLight 755 / S55-10

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-22444IR (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen CACNA1H
Clone S55-10
Host Mouse
Isotype IgG1
Conjugate DyLight 755
Target Species Human, Mouse, Rat
Applications WB, IHC, ICC/IF, IHC-P, IHC-Fr
Description Detects approx 260kDa. No cross-reactivity against Cav1.3.
About CACNA1H and DyLight 755
CACNA1H This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE). [provided by RefSeq, Jul 2008]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra