GDF-15 Polyclonal / Biotin /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP1-42732B (View supplier product page)
Size 0.1 ml
Price $659.00
Antigen GDF-15
Clone
Host Rabbit
Isotype IgG
Conjugate Biotin
Target Species Human, Mouse
Applications WB, ELISA, IHC
Description Partial reactivity is expected against swine, bovine and dog based on 92% identity. Cross-reactivity with NAG-1 from other sources has not been determined.
About GDF-15 and Biotin
GDF-15 This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The protein is expressed in a broad range of cell types, acts as a pleiotropic cytokine and is involved in the stress response program of cells after cellular injury. Increased protein levels are associated with disease states such as tissue hypoxia, inflammation, acute injury and oxidative stress. [provided by RefSeq, Aug 2016]
Images
  GDF-15 Biotin Novus Biologicals, a Bio-Techne brand antibody anti target:Human, Mouse host:Rabbit isotype:IgG clone: Western Blot: GDF15 Antibody [Biotin] [NBP1-42732B] - Detection of recombinant MBP-NAG-1 fusion p...

Western Blot: GDF15 Antibody [Biotin] [NBP1-42732B] - Detection of recombinant MBP-NAG-1 fusion protein (60 kDa) purified from E.coli (lane 1); yeast cell lysate expressing SUMO-mouse NAG-1 (42 kDa) (lane 2), and R&D human NAG-1 monomer purified from CHO-K1 cells (14 kDa) (lane 3). All lysates were run under reducing conditions.
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Biotin Excitation and Emission Spectra