CD8a Monoclonal / Biotin / AP-MAB0708

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-12183B (View supplier product page)
Size 100 μl
Price $479.00
Antigen CD8a
Clone AP-MAB0708
Host Rat
Isotype IgG2b
Conjugate Biotin
Target Species Mouse
Applications IHC, IHC-P
Description Rat CD8 antibody reacts with Mouse [Biotin]
About CD8a and Biotin
CD8a The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]
Citations
Additional
Sources
Reviews & Ratings
Submit a Review

Biotin Excitation and Emission Spectra