CD268 Monoclonal / Biotin / 7J21

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-22005B (View supplier product page)
Size 0.1 ml
Price $549.00
Antigen CD268
Clone 7J21
Host Rat
Isotype IgG2
Conjugate Biotin
Target Species Mouse
Applications ELISA, IHC, IHC-P
Description BAFFR/TNFRSF13C Antibody (7J21) [Biotin]
About CD268 and Biotin
CD268 B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq, Jul 2008]
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Biotin Excitation and Emission Spectra