gamma H2AX Polyclonal / Alexa Fluor 700 /

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NB100-384AF700 (View supplier product page)
Size 0.1 ml
Price $629.00
Antigen gamma H2AX
Clone
Host Rabbit
Isotype IgG
Conjugate Alexa Fluor 700
Target Species Canine, Human, Mouse, Rat
Applications WB, FC, IHC, ICC/IF, IHC-P, Knockout Validated
Description The epitope maps to a region surrounding phosphorylated serine 139 of human histone H2AX.
About gamma H2AX and Alexa Fluor 700
gamma H2AX Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-independent histone that is a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. [provided by RefSeq, Oct 2015]
Alexa Fluor 700 Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
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Alexa Fluor 700 Excitation and Emission Spectra