EPM2A Monoclonal / Alexa Fluor 488 / S84-37

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-42195AF488 (View supplier product page)
Size 100 μl
Price $449.00
Antigen EPM2A
Clone S84-37
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 488
Target Species Human
Applications WB, ICC/IF
Description Optimal dilution of this antibody should be experimentally determined.
About EPM2A and Alexa Fluor 488
EPM2A This gene encodes a dual-specificity phosphatase and may be involved in the regulation of glycogen metabolism. The protein acts on complex carbohydrates to prevent glycogen hyperphosphorylation, thus avoiding the formation of insoluble aggregates. Loss-of-function mutations in this gene have been associated with Lafora disease, a rare, adult-onset recessive neurodegenerative disease, which results in myoclonus epilepsy and usually results in death several years after the onset of symptoms. The disease is characterized by the accumulation of insoluble particles called Lafora bodies, which are derived from glycogen. [provided by RefSeq, Jan 2018]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra