Glypican 3 Monoclonal / Alexa Fluor 488 / GPC3/1534R

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-54468AF488 (View supplier product page)
Size 100 ul
Price $519.00
Antigen Glypican 3
Clone GPC3/1534R
Host Rabbit
Isotype IgG κ
Conjugate Alexa Fluor 488
Target Species Human, Rat
Applications FC, ICC/IF, IHC-P, IHC
Description Rabbit Glypican 3 antibody [Alexa Fluor 488] detects Human, Rat
About Glypican 3 and Alexa Fluor 488
Glypican 3 Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra