Glucagon Monoclonal / Alexa Fluor 488 / 49

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-23591AF488 (View supplier product page)
Size 0.1 ml
Price $509.00
Antigen Glucagon
Clone 49
Host Mouse
Isotype IgG1 κ
Conjugate Alexa Fluor 488
Target Species Human, Mammal
Applications WB, ELISA
Description Clone 49 binds human GLP-1(9-36)amide Based on inhibition ELISA, Clone 49 cross-reacts 3% with GLP-1(7-36)amide
About Glucagon and Alexa Fluor 488
Glucagon The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq, Jul 2008]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra