Amphiregulin Monoclonal / Alexa Fluor 488 / RM0151-7D17

Product Details
Supplier Novus Biologicals, a Bio-Techne brand
Catalog #: NBP2-12036AF488 (View supplier product page)
Size 0.1 ml
Price $569.00
Antigen Amphiregulin
Clone RM0151-7D17
Host Rat
Isotype IgG2
Conjugate Alexa Fluor 488
Target Species Mouse
Applications WB
Description This antibody detects mouse Amphiregulin in Western blotting.
About Amphiregulin and Alexa Fluor 488
Amphiregulin The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). The protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells, and it inhibits the growth of certain aggressive carcinoma cell lines. It also functions in mammary gland, oocyte and bone tissue development. This gene is associated with a psoriasis-like skin phenotype, and is also associated with other pathological disorders, including various types of cancers and inflammatory conditions. [provided by RefSeq, Apr 2014]
Alexa Fluor 488 Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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Alexa Fluor 488 Excitation and Emission Spectra