CD263 Polyclonal / Biotin /

Citations: (3)
Product Details
Supplier R&D Systems
Catalog #: BAF630 (View supplier product page)
Size 50 μg
Price $499.00
Antigen CD263
Clone
Host Goat
Isotype IgG
Conjugate Biotin
Target Species Human
Applications WB, ELISA, FC
Description Human TRAIL R3/TNFRSF10C Biotinylated Antibody
About CD263 and Biotin
CD263 The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]
Citations
PMID 17136498
PMID 17172403
PMID 19543058
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Biotin Excitation and Emission Spectra