CD169 Monoclonal / Alexa Fluor 488 / 908102
CD169 Monoclonal / Alexa Fluor 488 / 908102
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | FAB5197G-025 (View supplier product page) | |
| Size | 25 Tests | |
| Price | $179.00 | |
| Antigen | CD169 | |
| Clone | 908102 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | Alexa Fluor 488 | |
| Target Species | Human | |
| Applications | FC | |
| Description | Human Siglec-1/CD169 Alexa Fluor® 488-conjugated Antibody |
About CD169 and Alexa Fluor 488
| CD169 | This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| Alexa Fluor 488 | Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A. |
Images
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Detection of Siglec-1/CD169 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs), (A) resting, or (B) treated with 5 ng/mL Recombinant Human IFN-a (Catalog # 11100-1) overnight, were stained with Mouse Anti-Human Siglec-1/CD169 Alexa Fluor® 488-conjugated Monoclonal Antibody (Catalog # FAB5197G) and Mouse Anti-Human CD14 APC-conjugated Monoclonal Antibody (Catalog # FAB3832A). Quadrant markers were set based on control antibody staining (Catalog # IC002G). View our protocol for Staining Membrane-associated Proteins. |
Citations
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Reviews & Ratings
Alexa Fluor 488 Excitation and Emission Spectra
$179.00
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