PKC theta Monoclonal / Alexa Fluor 350 / 453416

Product Details
Supplier R&D Systems
Catalog #: IC4368U-100UG (View supplier product page)
Size 100 μg
Price $339.00
Antigen PKC theta
Clone 453416
Host Mouse
Isotype IgG2a
Conjugate Alexa Fluor 350
Target Species Human
Applications ICS
Description Human PKC theta Alexa Fluor® 350-conjugated Antibody
About PKC theta and Alexa Fluor 350
PKC theta Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008]
Alexa Fluor 350 Alexa Fluor™ 350 (AF350, Alexa 350) has an excitation peak at 346 nm and an emission peak at 442 nm, and is spectrally similar in size, brightness and application to AMCA, DyLight™ 350 and CF®350. Alexa 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 350 Excitation and Emission Spectra