Neurofilament Medium 160kDa Polyclonal / Unconjugated /
Neurofilament Medium 160kDa Polyclonal / Unconjugated /
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | AF3029 (View supplier product page) | |
| Size | 100 μg | |
| Price | $429.00 | |
| Antigen | Neurofilament Medium 160kDa | |
| Clone | ||
| Host | Sheep | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | WB, IHC, Knockout Validated | |
| Description | Human NF-M Antibody |
About Neurofilament Medium 160kDa and Purified
| Neurofilament Medium 160kDa | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008] |
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Images
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Western Blot Shows Human NF-M Specificity by Using Knockout Cell Line. Western blot shows lysates of HeLa human cervical epithelial carcinoma parental cell line and NF-M knockout HeLa cell line (KO). PVDF membrane was probed with 1 µg/mL of Sheep Anti-Human NF-M Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3029) followed by HRP-conjugated Anti-Sheep IgG Secondary Antibody (Catalog # HAF016). A specific band was detected for NF-M at approximately 155 kDa (as indicated) in the parental HeLa cell line, but is not detectable in knockout HeLa cell line. GAPDH (Catalog # AF5718) is shown as a loading control. This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1. |
Citations
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Purified Excitation and Emission Spectra
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