MSP Polyclonal / Unconjugated /

Product Details
Supplier R&D Systems
Catalog #: AF352-SP (View supplier product page)
Size 25 μg
Price $149.00
Antigen MSP
Clone
Host Goat
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse
Applications WB, Block/Neutralize, FC, IHC-P
Description Human MSP/MST1 Antibody
About MSP and Purified
MSP The protein encoded by this gene contains four kringle domains and a serine protease domain, similar to that found in hepatic growth factor. Despite the presence of the serine protease domain, the encoded protein may not have any proteolytic activity. The receptor for this protein is RON tyrosine kinase, which upon activation stimulates ciliary motility of ciliated epithelial lung cells. This protein is secreted and cleaved to form an alpha chain and a beta chain bridged by disulfide bonds. [provided by RefSeq, Jan 2010]
Images
  MSP Purified R&D Systems antibody anti target:Human, Mouse host:Goat isotype:IgG clone: Chemotaxis Induced by MSP and Neutralization by Human MSP Antibody. Recombinant Human MSP (Catalo...

Chemotaxis Induced by MSP and Neutralization by Human MSP Antibody. Recombinant Human MSP (Catalog # 352-MS) chemoattracts mouse peritoneal resident macrophages in a dose-dependent manner (orange line). The amount of cells that migrated through the filter was measured by LeukoStat™ staining (Fisher Scientific). Chemotaxis elicited by Recombinant Human MSP (50 ng/mL) is neutralized (green line) by increasing concentrations of Goat Anti-Human MSP Antigen Affinity-purified Polyclonal Antibody (Catalog # AF352). The ND50 is typically 0.05-0.2 µg/mL.

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Purified Excitation and Emission Spectra