MMP-12 Polyclonal / Unconjugated /
MMP-12 Polyclonal / Unconjugated /
Citations:
(2)
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | AF3467 (View supplier product page) | |
| Size | 100 μg | |
| Price | $479.00 | |
| Antigen | MMP-12 | |
| Clone | ||
| Host | Goat | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Mouse | |
| Applications | WB, IP | |
| Description | Mouse MMP-12 Antibody |
About MMP-12 and Purified
| MMP-12 | This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016] |
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Images
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Detection of Mouse MMP-12 by Western Blot. Western blot shows mouse serum and mouse plasma. PVDF membrane was probed with 2 µg/mL of Goat Anti-Mouse MMP-12 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3467) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). A specific band was detected for MMP-12 at approximately 55 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1. |
Citations
| PMID 18660381 | ||
|---|---|---|
| PMID 27917892 | ||
| Additional Sources |
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Reviews & Ratings
Purified Excitation and Emission Spectra
$479.00
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