CD85a Monoclonal / Alexa Fluor 405 / 222821

Product Details
Supplier R&D Systems
Catalog #: FAB1806V-100UG (View supplier product page)
Size 100 μg
Price $399.00
Antigen CD85a
Clone 222821
Host Mouse
Isotype IgG2a
Conjugate Alexa Fluor 405
Target Species Human
Applications FC
Description Human LILRB3/CD85a/ILT5 Alexa Fluor® 405-conjugated Antibody
About CD85a and Alexa Fluor 405
CD85a This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra