CD85a Monoclonal / Alexa Fluor 350 / 222821

Product Details
Supplier R&D Systems
Catalog #: FAB1806U-100UG (View supplier product page)
Size 100 μg
Price $399.00
Antigen CD85a
Clone 222821
Host Mouse
Isotype IgG2a
Conjugate Alexa Fluor 350
Target Species Human
Applications FC
Description Human LILRB3/CD85a/ILT5 Alexa Fluor® 350-conjugated Antibody
About CD85a and Alexa Fluor 350
CD85a This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Alexa Fluor 350 Alexa Fluor™ 350 (AF350, Alexa 350) has an excitation peak at 346 nm and an emission peak at 442 nm, and is spectrally similar in size, brightness and application to AMCA, DyLight™ 350 and CF®350. Alexa 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 350 Excitation and Emission Spectra