CD85a Monoclonal / Unconjugated / 222821
CD85a Monoclonal / Unconjugated / 222821
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | MAB1806-100 (View supplier product page) | |
| Size | 100 μg | |
| Price | $459.00 | |
| Antigen | CD85a | |
| Clone | 222821 | |
| Host | Mouse | |
| Isotype | IgG2a | |
| Conjugate | Unconjugated | |
| Target Species | Human, Mouse | |
| Applications | WB, FC, CyTOF, Block/Neutralize | |
| Description | Human LILRB3/CD85a/ILT5 Antibody |
About CD85a and Purified
| CD85a | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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Images
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Detection of LILRB3/CD85a/ILT5 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD14 PE-conjugated Monoclonal Antibody (Catalog # FAB3832P) and either (A) Mouse Anti-Human LILRB3/CD85a/ILT5 Monoclonal Antibody (Catalog # MAB1806) or (B) Mouse IgG2A Isotype Control (Catalog # MAB003) followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B). |
Citations
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Purified Excitation and Emission Spectra
$459.00
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