IL-18 Monoclonal / Alexa Fluor 700 / 74801

Product Details
Supplier R&D Systems
Catalog #: IC646N-100UG (View supplier product page)
Size 100 μg
Price $469.00
Antigen IL-18
Clone 74801
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 700
Target Species Human
Applications ICS
Description Human IL-18/IL-1F4 Propeptide Alexa Fluor® 700-conjugated Antibody
About IL-18 and Alexa Fluor 700
IL-18 The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020]
Alexa Fluor 700 Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
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Alexa Fluor 700 Excitation and Emission Spectra