IL-18 Polyclonal / Unconjugated /
IL-18 Polyclonal / Unconjugated /
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | AF588 (View supplier product page) | |
| Size | 100 μg | |
| Price | $469.00 | |
| Antigen | IL-18 | |
| Clone | ||
| Host | Goat | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Mouse, Porcine | |
| Applications | WB, ICC | |
| Description | Porcine IL-18/IL-1F4 Antibody |
About IL-18 and Purified
| IL-18 | The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2020] |
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Images
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IL-18/IL-1F4 in Porcine PBMCs. IL-18/IL-1F4 was detected in immersion fixed porcine peripheral blood mononuclear cells (PBMCs) using Goat Anti-Porcine IL-18/IL-1F4 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF588) at 15 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; Catalog # NL001) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. View our protocol for Fluorescent ICC Staining of Non-adherent Cells. |
Citations
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Purified Excitation and Emission Spectra
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