IL-13 Monoclonal / Alexa Fluor 350 / 31606

Product Details
Supplier R&D Systems
Catalog #: FAB2131U-100UG (View supplier product page)
Size 100 μg
Price $409.00
Antigen IL-13
Clone 31606
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 350
Target Species Human
Applications FC
Description Human IL-13 Alexa Fluor® 350-conjugated Antibody
About IL-13 and Alexa Fluor 350
IL-13 This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
Alexa Fluor 350 Alexa Fluor™ 350 (AF350, Alexa 350) has an excitation peak at 346 nm and an emission peak at 442 nm, and is spectrally similar in size, brightness and application to AMCA, DyLight™ 350 and CF®350. Alexa 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 350 Excitation and Emission Spectra