IL-10 R alpha Monoclonal / Alexa Fluor 647 / 714212
IL-10 R alpha Monoclonal / Alexa Fluor 647 / 714212
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | FAB2742R-100UG (View supplier product page) | |
| Size | 100 μg | |
| Price | $369.00 | |
| Antigen | IL-10 R alpha | |
| Clone | 714212 | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | Alexa Fluor 647 | |
| Target Species | Human | |
| Applications | FC | |
| Description | Human IL-10 R alpha Alexa Fluor® 647-conjugated Antibody |
About IL-10 R alpha and Alexa Fluor 647
| IL-10 R alpha | The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009] | |
|---|---|---|
| Alexa Fluor 647 | Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye. |
Images
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Detection of IL-10 R alpha in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with (A) Mouse Anti-Human IL-10 R alpha Alexa Fluor® 647-conjugated Monoclonal Antibody (Catalog # FAB2742R) or (B) Mouse IgG2B isotype control antibody (Catalog # IC0041R) and Mouse Anti-Human CD19 PE-conjugated Monoclonal Antibody(Catalog # FAB4867P). View our protocol for Staining Membrane-associated Proteins. |
Citations
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Reviews & Ratings
Alexa Fluor 647 Excitation and Emission Spectra
$369.00
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