IL-10 R alpha Monoclonal / Alexa Fluor 594 / 714212

Product Details
Supplier R&D Systems
Catalog #: FAB2742T-100UG (View supplier product page)
Size 100 μg
Price $349.00
Antigen IL-10 R alpha
Clone 714212
Host Mouse
Isotype IgG2b
Conjugate Alexa Fluor 594
Target Species Human
Applications FC
Description Human IL-10 R alpha Alexa Fluor® 594-conjugated Antibody
About IL-10 R alpha and Alexa Fluor 594
IL-10 R alpha The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene. [provided by RefSeq, Jan 2009]
Alexa Fluor 594 Alexa Fluor™ 594 (AF594, Alexa 594) has an excitation peak at 590 nm and an emission peak at 617 nm, and is spectrally similar to Texas Red (ThermoFisher Scientific), DyLight™ 594 (ThermoFisher Scientific), iFluor® 594 (ATT Bioquest) and iFluor® 610 (ATT Bioquest), CF®594 (Biotium), and ATTO 594 (ATTO-TEC). Alexa 594 is commonly used for flow cytometry,fluorescence microscopy and super-resolution microscopy. It is very bright, photostable, and pH insensitive.
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Alexa Fluor 594 Excitation and Emission Spectra