CD130 Monoclonal / Alexa Fluor 405 / 745314

Product Details
Supplier R&D Systems
Catalog #: FAB5029V-100UG (View supplier product page)
Size 100 μg
Price $449.00
Antigen CD130
Clone 745314
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 405
Target Species Rat
Applications FC
Description Rat gp130 Alexa Fluor® 405-conjugated Antibody
About CD130 and Alexa Fluor 405
CD130 The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra