GFR alpha-1 Monoclonal / Unconjugated / 260714

Citations: (1)
Product Details
Supplier R&D Systems
Catalog #: MAB7141 (View supplier product page)
Size 100 μg
Price $429.00
Antigen GFR alpha-1
Clone 260714
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Target Species Human, Rhesus macaque
Applications WB, IHC-P
Description Human GFR alpha-1/GDNF R alpha-1 Antibody
About GFR alpha-1 and Purified
GFR alpha-1 This gene encodes a member of the glial cell line-derived neurotrophic factor receptor (GDNFR) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature receptor. Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. This receptor is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016]
Citations
PMID 17585169
Additional
Sources
Reviews & Ratings
Submit a Review

Purified Excitation and Emission Spectra