FGF-4 Monoclonal / Unconjugated / 19805
FGF-4 Monoclonal / Unconjugated / 19805
Citations:
(1)
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | MAB235 (View supplier product page) | |
| Size | 500 μg | |
| Price | $549.00 | |
| Antigen | FGF-4 | |
| Clone | 19805 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | Unconjugated | |
| Target Species | Human, Rat | |
| Applications | WB, Block/Neutralize, IP, IHC-P | |
| Description | Human FGF-4 Antibody |
About FGF-4 and Purified
| FGF-4 | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified by its oncogenic transforming activity. This gene and FGF3, another oncogenic growth factor, are located closely on chromosome 11. Co-amplification of both genes was found in various kinds of human tumors. Studies on the mouse homolog suggested a function in bone morphogenesis and limb development through the sonic hedgehog (SHH) signaling pathway. [provided by RefSeq, Jul 2008] |
|---|
Images
|
Cell Proliferation Induced by FGF-4 and Neutralization by Human FGF-4 Antibody. Recombinant Human FGF-4 (Catalog # 235-F4) stimulates proliferation in the NR6R-3T3 mouse fibroblast cell line in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Human FGF-4 (0.5 ng/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human FGF-4 Monoclonal Antibody (Catalog # MAB235). The ND50 is typically 5-8 µg/mL. |
Citations
| PMID 8550832 | ||
|---|---|---|
| Additional Sources |
|
Reviews & Ratings
Purified Excitation and Emission Spectra
$549.00
Supplier Page
Supplier Page
