EphB2 Monoclonal / Alexa Fluor 350 / 512012

Product Details
Supplier R&D Systems
Catalog #: FAB467U-100UG (View supplier product page)
Size 100 μg
Price $399.00
Antigen EphB2
Clone 512012
Host Rat
Isotype IgG2a
Conjugate Alexa Fluor 350
Target Species Human, Mouse
Applications FC
Description Human/Mouse EphB2 Alexa Fluor® 350-conjugated Antibody
About EphB2 and Alexa Fluor 350
EphB2 This gene encodes a member of the Eph receptor family of receptor tyrosine kinase transmembrane glycoproteins. These receptors are composed of an N-terminal glycosylated ligand-binding domain, a transmembrane region and an intracellular kinase domain. They bind ligands called ephrins and are involved in diverse cellular processes including motility, division, and differentiation. A distinguishing characteristic of Eph-ephrin signaling is that both receptors and ligands are competent to transduce a signaling cascade, resulting in bidirectional signaling. This protein belongs to a subgroup of the Eph receptors called EphB. Proteins of this subgroup are distinguished from other members of the family by sequence homology and preferential binding affinity for membrane-bound ephrin-B ligands. Allelic variants are associated with prostate and brain cancer susceptibility. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]
Alexa Fluor 350 Alexa Fluor™ 350 (AF350, Alexa 350) has an excitation peak at 346 nm and an emission peak at 442 nm, and is spectrally similar in size, brightness and application to AMCA, DyLight™ 350 and CF®350. Alexa 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 350 Excitation and Emission Spectra