CX3CL1 Monoclonal / PE / 126315

Product Details
Supplier R&D Systems
Catalog #: FAB571P-025 (View supplier product page)
Size 25 Tests
Price $229.00
Antigen CX3CL1
Clone 126315
Host Rat
Isotype IgG2a
Conjugate PE
Target Species Mouse
Applications FC
Description Mouse CX3CL1/Fractalkine PE-conjugated Antibody
About CX3CL1 and PE
CX3CL1 This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections. [provided by RefSeq, Sep 2017]
PE Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.
Images
  CX3CL1 PE R&D Systems antibody anti target:Mouse host:Rat isotype:IgG2a clone:126315 Detection of CX3CL1/Fractalkine in bEnd.3 Mouse Cell Line by Flow Cytometry. bEnd.3 mouse endothe...

Detection of CX3CL1/Fractalkine in bEnd.3 Mouse Cell Line by Flow Cytometry. bEnd.3 mouse endothelioma cell line was stained with Rat Anti-Mouse CX3CL1/Fractalkine PE-conjugated Monoclonal Antibody (Catalog # FAB571P, filled histogram) or isotype control antibody (Catalog # IC006P, open histogram). View our protocol for Staining Membrane-associated Proteins.

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PE Excitation and Emission Spectra