CX3CL1 Monoclonal / Alexa Fluor 488 / 126315
CX3CL1 Monoclonal / Alexa Fluor 488 / 126315
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | FAB571G-025 (View supplier product page) | |
| Size | 25 Tests | |
| Price | $195.00 | |
| Antigen | CX3CL1 | |
| Clone | 126315 | |
| Host | Rat | |
| Isotype | IgG2a | |
| Conjugate | Alexa Fluor 488 | |
| Target Species | Mouse | |
| Applications | FC |
About CX3CL1 and Alexa Fluor 488
| CX3CL1 | This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections. [provided by RefSeq, Sep 2017] | |
|---|---|---|
| Alexa Fluor 488 | Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A. |
Images
|
Detection of CX3CL1/Fractalkine in bEnd.3 Mouse Cell Line by Flow Cytometry. bEnd.3 mouse endothelioma cell line was stained with Rat Anti-Mouse CX3CL1/Fractalkine Alexa Fluor® 488-conjugated Monoclonal Antibody (Catalog # FAB571G, filled histogram) or isotype control antibody (Catalog # IC006G, open histogram). View our protocol for Staining Membrane-associated Proteins. |
Citations
| Additional Sources |
|
|---|
Reviews & Ratings
Alexa Fluor 488 Excitation and Emission Spectra
$195.00
Supplier Page
Supplier Page
