CX3CL1 Monoclonal / Unconjugated / 51637

Citations: (8)
Product Details
Supplier R&D Systems
Catalog #: MAB365-100 (View supplier product page)
Size 100 μg
Price $459.00
Antigen CX3CL1
Clone 51637
Host Mouse
Isotype IgG1
Conjugate Unconjugated
Target Species Human
Applications CyTOF, FC, IHC, WB, IHC-Fr, Block/Neutralize, ICFC, ICC, Functional
Description Human CX3CL1/Fractalkine Chemokine Domain Antibody Intracellular Flow Cytometry = ICFC
About CX3CL1 and Purified
CX3CL1 This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections. [provided by RefSeq, Sep 2017]
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Purified Excitation and Emission Spectra