C-Myc Monoclonal / Alexa Fluor 750 / 9.00E+10
C-Myc Monoclonal / Alexa Fluor 750 / 9.00E+10
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | IC3696S-100UG (View supplier product page) | |
| Size | 100 μg | |
| Price | $419.00 | |
| Antigen | C-Myc | |
| Clone | 9.00E+10 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | Alexa Fluor 750 | |
| Target Species | Human | |
| Applications | ICS | |
| Description | Human c-Myc Alexa Fluor® 750-conjugated Antibody |
About C-Myc and Alexa Fluor 750
| C-Myc | This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017] | |
|---|---|---|
| Alexa Fluor 750 | Alexa Fluor™ 750 (AF750, Alexa 750) has an excitation peak at 749 nm and an emission peak at 775 nm, and is spetrally similar to Cy®7 (GE Healthcare), APC-Fire™ 750 (BioLegend), CF®®750 (Biotium), DyLight™ 750 (ThermoFisher Scientific), iFluor® 750 (ATT Bioquest) and iFluor® 790 (ATT Bioquest). Alexa 750 is often used as a tandem fluorophore in flow cytometry or used on its own in fluorescence microscopy, in-vivo fluorescence microscopy or super-resolution microscopy applications. |
Images
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Detection of c-Myc in Jurkat Human Cell Line by Flow Cytometry. Jurkat human acute T cell leukemia cell line was stained with Mouse Anti-Human c-Myc Alexa Fluor® 750-conjugated Monoclonal Antibody (Catalog # IC3696S, filled histogram) or isotype control antibody (Catalog # IC002S, open histogram). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with methanol. View our protocol for Staining Intracellular Molecules. |
Citations
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Reviews & Ratings
Alexa Fluor 750 Excitation and Emission Spectra
$419.00
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