Claudin-12 Monoclonal / Alexa Fluor 700 / 393314

Product Details
Supplier R&D Systems
Catalog #: FAB4284N-100UG (View supplier product page)
Size 100 μg
Price $329.00
Antigen Claudin-12
Clone 393314
Host Mouse
Isotype IgG2a
Conjugate Alexa Fluor 700
Target Species Human
Applications FC
Description Human Claudin-12 Alexa Fluor® 700-conjugated Antibody
About Claudin-12 and Alexa Fluor 700
Claudin-12 This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in the inner ear and bladder epithelium, and it is over-expressed in colorectal carcinomas. This protein and claudin 2 are critical for vitamin D-dependent Ca2+ absorption between enterocytes. Multiple alternatively spliced transcript variants encoding the same protein have been found.[provided by RefSeq, Sep 2011]
Alexa Fluor 700 Alexa Fluor™ 700 (AF700, Alexa 700) has an excitation peak at 702 nm and an emission peak at 723 nm, and is spectrally similar to iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 700 is commonly used in Flow Cytometry and is similar in size, brightness and application to iFluor® 700 and Vio® R720.
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Alexa Fluor 700 Excitation and Emission Spectra