CD8a Monoclonal / PerCP / 37006
CD8a Monoclonal / PerCP / 37006
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | FAB1509C-100 (View supplier product page) | |
| Size | 100 Tests | |
| Price | $309.00 | |
| Antigen | CD8a | |
| Clone | 37006 | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | PerCP | |
| Target Species | Human | |
| Applications | FC | |
| Description | Human CD8 alpha PerCP-conjugated Antibody |
About CD8a and PerCP
| CD8a | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020] | |
|---|---|---|
| PerCP | Peridinin-Chlorophyll-Protein (PerCP) is a red-emitting fluorescent protein isolated from algae that can be excited by the 488 nm blue laser and captured with a 670/30 nm bandpass filter. PerCP exhibits a large Stokes' Shift, with an excitation peak at 482 nm and an emission peak at 675 nm. PerCP is was historically used in flow cytometry, however it is highly susceptible to photobleaching and has poor stability. Alternatives like BB700, NovaFluor Blue 690 or PerCP-eFluor™ 710 are preferred. PerCP is a generic dye that has no sole manufacturer. |
Images
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Detection of CD8 alpha in Human Blood Lymphocytes by Flow Cytometry. Human peripheral blood lymphocytes were stained with Mouse Anti-Human CD8 alpha PerCP-conjugated Monoclonal Antibody (Catalog # FAB1509C, filled histogram) or isotype control antibody (Catalog # IC0041C, open histogram). View our protocol for Staining Membrane-associated Proteins. |
Citations
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Reviews & Ratings
PerCP Excitation and Emission Spectra
$309.00
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