CD8a Monoclonal / Alexa Fluor 405 / 37006
CD8a Monoclonal / Alexa Fluor 405 / 37006
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | FAB1509V-025 (View supplier product page) | |
| Size | 25 Tests | |
| Price | $129.00 | |
| Antigen | CD8a | |
| Clone | 37006 | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | Alexa Fluor 405 | |
| Target Species | Human | |
| Applications | FC | |
| Description | Human CD8 alpha Alexa Fluor 405-conjugated Antibody |
About CD8a and Alexa Fluor 405
| CD8a | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020] | |
|---|---|---|
| Alexa Fluor 405 | Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications. |
Images
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Detection of CD8 alpha in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) were stained with Mouse Anti-Human CD3 epsilon APC-conjugated Monoclonal Antibody (Catalog # FAB100A) and either (A) Mouse Anti-Human CD8 alpha Alexa Fluor® 405-conjugated Monoclonal Antibody (Catalog # FAB1509V) or (B) Mouse IgG2B Alexa Fluor 405 Isotype Control (Catalog # IC0041V). View our protocol for Staining Membrane-associated Proteins. |
Citations
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Reviews & Ratings
Alexa Fluor 405 Excitation and Emission Spectra
$129.00
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