CD46 Monoclonal / Alexa Fluor 405 / 344519

Product Details
Supplier R&D Systems
Catalog #: FAB2005V-100UG (View supplier product page)
Size 100 μg
Price $319.00
Antigen CD46
Clone 344519
Host Mouse
Isotype IgG2b
Conjugate Alexa Fluor 405
Target Species Human
Applications FC
Description Human CD46 Alexa Fluor® 405-conjugated Antibody
About CD46 and Alexa Fluor 405
CD46 The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. Mutations at this locus have been associated with susceptibility to hemolytic uremic syndrome. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra