CD45 Monoclonal / Alexa Fluor 405 / 30-F11
CD45 Monoclonal / Alexa Fluor 405 / 30-F11
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | FAB114V-025 (View supplier product page) | |
| Size | 25 Tests | |
| Price | $159.00 | |
| Antigen | CD45 | |
| Clone | 30-F11 | |
| Host | Rat | |
| Isotype | IgG2b | |
| Conjugate | Alexa Fluor 405 | |
| Target Species | Human, Mouse | |
| Applications | FC, ICC | |
| Description | Mouse CD45 Alexa Fluor® 405-conjugated Antibody |
About CD45 and Alexa Fluor 405
| CD45 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012] | |
|---|---|---|
| Alexa Fluor 405 | Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications. |
Images
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Detection of CD45 in Mouse Bone Marrow Cells by Flow Cytometry. Mouse bone marrow cells were stained with Rat Anti-Mouse TER-119 APC-conjugated Monoclonal Antibody (Catalog # FAB1125A) and either (A) Rat Anti-Mouse CD45 Alexa Fluor® 405-conjugated Monoclonal Antibody (Catalog # FAB114V) or (B) Rat IgG2B Alexa Fluor 405 Isotype Control (Catalog # IC013V). View our protocol for Staining Membrane-associated Proteins. |
Citations
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Reviews & Ratings
Alexa Fluor 405 Excitation and Emission Spectra
$159.00
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