CD11b Monoclonal / Alexa Fluor 750 / M1/70
CD11b Monoclonal / Alexa Fluor 750 / M1/70
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | FAB1124S-025 (View supplier product page) | |
| Size | 25 Tests | |
| Price | $149.00 | |
| Antigen | CD11b | |
| Clone | M1/70 | |
| Host | Rat | |
| Isotype | IgG2b | |
| Conjugate | Alexa Fluor 750 | |
| Target Species | Mouse | |
| Applications | FC | |
| Description | Mouse Integrin alpha M/CD11b Alexa Fluor® 750-conjugated Antibody |
About CD11b and Alexa Fluor 750
| CD11b | This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] | |
|---|---|---|
| Alexa Fluor 750 | Alexa Fluor™ 750 (AF750, Alexa 750) has an excitation peak at 749 nm and an emission peak at 775 nm, and is spetrally similar to Cy®7 (GE Healthcare), APC-Fire™ 750 (BioLegend), CF®®750 (Biotium), DyLight™ 750 (ThermoFisher Scientific), iFluor® 750 (ATT Bioquest) and iFluor® 790 (ATT Bioquest). Alexa 750 is often used as a tandem fluorophore in flow cytometry or used on its own in fluorescence microscopy, in-vivo fluorescence microscopy or super-resolution microscopy applications. |
Images
|
Detection of Integrin alpha M/CD11b in Mouse Bone Marrow Cells by Flow Cytometry. Mouse bone marrow cells were stained with Rat Anti-Mouse Gr-1/Ly-6G PE-conjugated Monoclonal Antibody (Catalog # FAB1037P) and either (A) Rat Anti-Mouse Integrin alpha M/CD11b Alexa Fluor® 750-conjugated Monoclonal Antibody (Catalog # FAB1124S) or (B) Rat IgG2B Alexa Fluor 750 Isotype Control (Catalog # IC013S). View our protocol for Staining Membrane-associated Proteins. |
Citations
| Additional Sources |
|
|---|
Reviews & Ratings
Alexa Fluor 750 Excitation and Emission Spectra
$149.00
Supplier Page
Supplier Page
