CCL1 Monoclonal / Unconjugated / 148107
CCL1 Monoclonal / Unconjugated / 148107
Citations:
(3)
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | MAB8451 (View supplier product page) | |
| Size | 500 μg | |
| Price | $559.00 | |
| Antigen | CCL1 | |
| Clone | 148107 | |
| Host | Rat | |
| Isotype | IgG2b | |
| Conjugate | Unconjugated | |
| Target Species | Mouse | |
| Applications | ELISA, Block/Neutralize, Functional | |
| Description | Mouse CCL1/I-309/TCA-3 Antibody |
About CCL1 and Purified
| CCL1 | This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8. [provided by RefSeq, Sep 2014] |
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Images
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Chemotaxis Induced by CCL1/I-309/TCA-3 and Neutralization by Mouse CCL1/I-309/TCA-3 Antibody. Recombinant Mouse CCL1/TCA-3 (Catalog # 845-TC) chemoattracts the BaF3 mouse pro-B cell line transfected with mouse CCR8 in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin (Catalog # AR002). Chemotaxis elicited by Recombinant Mouse CCL1/TCA-3 (10 ng/mL) is neutralized (green line) by increasing concentrations of Rat Anti-Mouse CCL1/I-309/ TCA-3 Monoclonal Antibody (Catalog # MAB8451). The ND50 is typically 0.6-3.0 µg/mL. |
Citations
| PMID 18672278 | ||
|---|---|---|
| PMID 22277799 | ||
| PMID 25485859 | ||
| Additional Sources |
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Reviews & Ratings
Purified Excitation and Emission Spectra
$559.00
Supplier Page
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