CCL1 Monoclonal / Unconjugated / 35305
CCL1 Monoclonal / Unconjugated / 35305
Citations:
(2)
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | MAB272-100 (View supplier product page) | |
| Size | 100 μg | |
| Price | $459.00 | |
| Antigen | CCL1 | |
| Clone | 35305 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | WB, ELISA, Block/Neutralize, ICC | |
| Description | Human CCL1/I-309/TCA-3 Antibody |
About CCL1 and Purified
| CCL1 | This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8. [provided by RefSeq, Sep 2014] |
|---|
Images
|
Chemotaxis Induced by CCL1/I-309 and Neutralization by Human CCL1/I-309 Anti-body. Recombinant Human CCL1/I-309 (Catalog # 272-I) chemoattracts the BaF3 mouse pro-B cell line transfected with human CCR8 in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin (Catalog # AR002). Chemotaxis elicited by Recombinant Human CCL1/I-309 (0.02 µg/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human CCL1/I-309 Monoclonal Antibody (Catalog # MAB272). The ND50 is typically 0.1-0.5 µg/mL. |
Citations
| Additional Sources |
|
|---|
Reviews & Ratings
Purified Excitation and Emission Spectra
$459.00
Supplier Page
Supplier Page
