BMP-8b Monoclonal / Unconjugated / 158708

Product Details
Supplier R&D Systems
Catalog #: MAB1073 (View supplier product page)
Size 500 μg
Price $559.00
Antigen BMP-8b
Clone 158708
Host Mouse
Isotype IgG2b
Conjugate Unconjugated
Target Species Human
Applications WB
Description Human BMP-8 Antibody
About BMP-8b and Purified
BMP-8b This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. The encoded protein stimulates thermogenesis in brown adipose tissue. Expression of this gene may be downregulated in pancreatic cancer. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. [provided by RefSeq, Jul 2016]
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Purified Excitation and Emission Spectra