CD239 Polyclonal / Unconjugated /
CD239 Polyclonal / Unconjugated /
Product Details
| Supplier | R&D Systems | |
|---|---|---|
| Catalog #: | AF148-SP (View supplier product page) | |
| Size | 25 μg | |
| Price | $149.00 | |
| Antigen | CD239 | |
| Clone | ||
| Host | Goat | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | WB, Block, FC, Block/Neutralize | |
| Description | Human BCAM Antibody |
About CD239 and Purified
| CD239 | This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Polymorphisms in this gene define some of the antigens in the Lutheran system and also the Auberger system. Inactivating variants of this gene result in the recessive Lutheran null phenotype, Lu(a-b-), of the Lutheran blood group. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012] |
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Images
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Detection of Human BCAM by Western Blot. Western blot shows lysates of LNCaP human prostate cancer cell line, human prostate tissue, human kidney tissue, and human thyroid tissue. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human BCAM Antigen Affinity-purified Polyclonal Antibody (Catalog # AF148) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF017). Specific bands were detected for BCAM at approximately 70-90 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1. |
Citations
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Purified Excitation and Emission Spectra
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