CD86 Monoclonal / Alexa Fluor 405 / 37301

Product Details
Supplier R&D Systems
Catalog #: FAB141V-100UG (View supplier product page)
Size 100 μg
Price $389.00
Antigen CD86
Clone 37301
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 405
Target Species Human
Applications FC
Description Human B7-2/CD86 Alexa Fluor® 405-conjugated Antibody
About CD86 and Alexa Fluor 405
CD86 This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra