CD86 Monoclonal / Alexa Fluor 350 / GL1

Product Details
Supplier R&D Systems
Catalog #: FAB741U-100UG (View supplier product page)
Size 100 μg
Price $349.00
Antigen CD86
Clone GL1
Host Rat
Isotype IgG2a
Conjugate Alexa Fluor 350
Target Species Mouse
Applications FC
Description Mouse B7-2/CD86 Alexa Fluor® 350-conjugated Antibody
About CD86 and Alexa Fluor 350
CD86 This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]
Alexa Fluor 350 Alexa Fluor™ 350 (AF350, Alexa 350) has an excitation peak at 346 nm and an emission peak at 442 nm, and is spectrally similar in size, brightness and application to AMCA, DyLight™ 350 and CF®350. Alexa 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 350 Excitation and Emission Spectra